Editing Instem plc: Holding(s) in Company

'''Issuer Details'''
{| class="wikitable"
|+
|ISIN:
|GB00B3TQCK30
|-
|Issuer Name:
|Instem plc
|-
|UK or Non-UK Issuer:
|UK
|}
What's the reason for the notification? An acquisition or disposal of voting rights.

'''Details of person subject to the notification obligation'''
{| class="wikitable"
|+
!
!
|-
|Name
|Liontrust Investment Partners LLP
|-
|City of registered office (if applicable)
|NA
|-
|Country of registered office (if applicable)
|Great Britain
|}
'''Details of the shareholder'''
{| class="wikitable"
|+
!Name
!City of registered office
!Country of registered office
|-
|Liontrust Asset Management Plc
|London
|United Kingdom
|}
'''On which date was the threshold crossed or reached?''' 28th June 2022.

'''On which date was the Issuer notified?''' 29th June 2022.

'''Total positions of person(s) subject to the notification obligation'''
{| class="wikitable"
|+
!
!% of voting rights attached to shares (total of 8.A)
!% of voting rights through financial instruments (total of 8.B 1 + 8.B 2)
!Total of both in % (8.A + 8.B)
!Total number of voting rights held in issuer
|-
|Resulting situation on the date on which threshold was crossed or reached
|11.088000
|0.000000
|11.088000
|2514290
|-
|Position of previous notification (if applicable)
|10.022000
|0.036000
|10.058000
|
|}
'''Notified details of the resulting situation on the date on which the threshold was crossed or reached: Voting rights attached to shares'''
{| class="wikitable"
|+
!Class/Type of shares ISIN code(if possible)
!Number of direct voting rights (DTR5.1)
!Number of indirect voting rights (DTR5.2.1)
!% of direct voting rights (DTR5.1)
!% of indirect voting rights (DTR5.2.1)
|-
|GB00B3TQCK30
|2514290
|
|11.088000
|
|-
|Sub Total 8.A
| colspan="2" |2514290
| colspan="2" |11.088000%
|}


'''Information in relation to the person subject to the notification obligation'''

Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities.
{| class="wikitable"
|+
!Ultimate controlling person
!Name of controlled undertaking
!% of voting rights if it equals or is higher than the notifiable threshold
!% of voting rights through financial instruments if it equals or is higher than the notifiable threshold
!Total of both if it equals or is higher than the notifiable threshold
|-
|Liontrust Asset Management Plc
|Liontrust Investment Partners LLP
|11.088000
|
|11.088000%
|}
'''On which date was completion?''' 29th June 2022.

'''In which place was completion?''' London.