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crizotinib English (Q5186964)

Item Discussion
chemical compound
edit
Language Label Description Also known as
British English
No label defined
chemical compound

    Statements

    Freebase ID
    /m/0c418c1
    1 reference
    stated in
    Q15241312 (Deleted Item)
    publication date
    28 October 2013
    CAS registry number
    877399-52-5
    2 references
    stated in
    Unique Ingredient Identifier English
    UNII English
    53AH36668S
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 November 2016
    InChIKey
    KTEIFNKAUNYNJU-GFCCVEGCSA-N
    stated in
    Q18907859 (Deleted Item)
    retrieved
    8 April 2021
    reference URL
    https://commonchemistry.cas.org/detail?cas_rn=877399-52-5
    PubChem CID
    11626560
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    11626560
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 November 2016
    chemical formula
    C₂₁H₂₂Cl₂FN₅O
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    11626560
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 November 2016
    InChI
    InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    11626560
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 November 2016
    InChIKey
    KTEIFNKAUNYNJU-GFCCVEGCSA-N
    2 references
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    11626560
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 November 2016
    stated in
    Q98915402 (Deleted Item)
    ChEMBL ID
    CHEMBL601719
    1 reference
    stated in
    ChEMBL English
    ChEMBL ID
    CHEMBL601719
    language of work or name
    English
    title
    CRIZOTINIB (English)
    retrieved
    19 November 2016
    KEGG ID English
    D09731
    1 reference
    stated in
    Q902623 (Deleted Item)
    ChEBI ID
    64310
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 October 2016
    ChemSpider ID
    9801307
    1 reference
    stated in
    ChemSpider
    ChemSpider ID
    9801307
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 October 2016
    UNII English
    53AH36668S
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    53AH36668S
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 November 2016
    ATC code English
    L01XE16
    1 reference
    stated in
    Q1122544 (Deleted Item)
    DrugBank ID English
    08865
    language of work or name
    English
    title
    Crizotinib (English)
    publication date
    17 November 2015
    ChEBI ID
    64310
    mapping relation type English
    exact match English
    1 reference
    stated in
    ChEMBL English
    ChEMBL ID
    CHEMBL601719
    language of work or name
    English
    title
    CRIZOTINIB (English)
    retrieved
    19 November 2016
    Guide to Pharmacology Ligand ID English
    4903
    1 reference
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    4903
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 November 2016
    NDF-RT ID English
    N0000183253
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    53AH36668S
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 November 2016
    SMILES
    CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    11626560
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 November 2016
    isomeric SMILES
    C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    11626560
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 November 2016
    ECHA InfoCard ID
    100.166.440
    1 reference
    stated in
    Q59911453 (Deleted Item)
    ECHA InfoCard ID
    100.166.440
    retrieved
    27 December 2018
    title
    2-Pyridinamine,3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl] (English)
    quotation
    CAS no.: 877399-52-5 (English)
    Reaxys registry number English
    12133926
    1 reference
    stated in
    Q902623 (Deleted Item)
    ChEBI ID
    64310
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 October 2016
    World Health Organisation international non-proprietary name English
    crizotinib (English)
    1 reference
    stated in
    Q902623 (Deleted Item)
    ChEBI ID
    64310
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 October 2016
    PDB structure ID English
    4C9W
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    4C9W
    language of work or name
    English
    title
    4C9W (English)
    retrieved
    19 October 2016
    2WGJ
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    2WGJ
    language of work or name
    English
    title
    2WGJ (English)
    retrieved
    19 October 2016
    3ZBF
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    3ZBF
    language of work or name
    English
    title
    3ZBF (English)
    retrieved
    19 October 2016
    5AAA
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    5AAA
    language of work or name
    English
    title
    5AAA (English)
    retrieved
    19 October 2016
    5AAC
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    5AAC
    language of work or name
    English
    title
    5AAC (English)
    retrieved
    19 October 2016
    5AAB
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    5AAB
    language of work or name
    English
    title
    5AAB (English)
    retrieved
    19 October 2016
    2XP2
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    2XP2
    language of work or name
    English
    title
    2XP2 (English)
    retrieved
    19 October 2016
    4ANS
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    4ANS
    language of work or name
    English
    title
    4ANS (English)
    retrieved
    19 October 2016
    4ANQ
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    4ANQ
    language of work or name
    English
    title
    4ANQ (English)
    retrieved
    19 October 2016
    2YFX
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    2YFX
    language of work or name
    English
    title
    2YFX (English)
    retrieved
    19 October 2016
    DrugBank ID English
    08865
    0 references
    mass
    449.119±0 http://www.wikidata.org/entity/Q483261
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    11626560
    language of work or name
    English
    title
    Crizotinib (English)
    retrieved
    19 October 2016
    RxNorm ID English
    1148495
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    53AH36668S
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 November 2016
    UMLS CUI English
    C2974289
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    53AH36668S
    language of work or name
    English
    title
    crizotinib (English)
    retrieved
    19 November 2016
    active ingredient in English
    Q29006680 (Deleted Item)
    1 reference
    stated in
    RxNorm English
    RxNorm ID English
    1148499
    retrieved
    14 February 2018
    subject has role
    Q50348938 (Deleted Item)
    1 reference
    stated in
    Q21008030 (Deleted Item)
    NDF-RT ID English
    N0000183253
    retrieved
    5 March 2018
    protein kinase inhibitors English
    1 reference
    stated in
    Q199897 (Deleted Item)
    MeSH
    C551994
    retrieved
    15 March 2018
    MeSH
    D000077547
    named as
    Crizotinib
    0 references
    medical condition treated
    inflammatory myofibroblastic tumour English
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    non-small-cell lung carcinoma English
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q18556109 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q55998694 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    EC number
    638-814-9
    1 reference
    stated in
    Q59911453 (Deleted Item)
    ECHA InfoCard ID
    100.166.440
    retrieved
    27 December 2018
    title
    2-Pyridinamine,3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl] (English)
    quotation
    CAS no.: 877399-52-5 (English)
    physically interacts with
    Q21111336 (Deleted Item)
    subject has role
    Q427492 (Deleted Item)
    1 reference
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    4903
    language of work or name
    English
    retrieved
    17 August 2016
    MET proto-oncogene, receptor tyrosine kinase English
    subject has role
    Q427492 (Deleted Item)
    1 reference
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    4903
    language of work or name
    English
    retrieved
    17 August 2016
    SPLASH English
    splash10-0udi-1693800000-fc52c38f3359a378554a
    0 references
    MeSH Code
    D03.383.621.154
    0 references
    D03.383.725.050.263
    0 references
    DSSTox substance ID English
    DTXSID701009329
    0 references
    LiverTox ID English
    Crizotinib
    0 references
    NSC number English
    756645
    0 references
    Microsoft Academic ID
    2779422266
    0 references
    DSSTOX compound identifier English
    DTXCID601436157
    0 references
    PDB ligand ID English
    VGH
    0 references
    LiverTox likelihood score English
    Q83284310 (Deleted Item)
    1 reference
    stated in
    Q78239405 (Deleted Item)
    retrieved
    8 April 2021
    reference URL
    https://www.ncbi.nlm.nih.gov/books/n/livertox/Crizotinib
    last update English
    30 October 2017
    MedlinePlus drug identifier English
    a612018
    0 references
    PatientsLikeMe treatment ID English
    crizotinib
    0 references
    Commons category
    Crizotinib
    0 references
    P11199 (Deleted Property)
    PD003326 Property P11199 not found, cannot determine the data type to use.
    0 references
    P11143 (Deleted Property)
    Crizotinib Property P11143 not found, cannot determine the data type to use.
    0 references
     
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