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Ruxolitinib (Q7383611)

Item Discussion
chemical compound
edit
Language Label Description Also known as
British English
Ruxolitinib
chemical compound

    Statements

    CAS registry number
    941678-49-5
    2 references
    stated in
    Unique Ingredient Identifier English
    UNII English
    82S8X8XX8H
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    20 November 2016
    InChIKey
    HFNKQEVNSGCOJV-OAHLLOKOSA-N
    stated in
    Q18907859 (Deleted Item)
    retrieved
    9 April 2021
    reference URL
    https://commonchemistry.cas.org/detail?cas_rn=941678-49-5
    PubChem CID
    25126798
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    25126798
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    chemical formula
    C₁₇H₁₈N₆
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    25126798
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    InChI
    InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    25126798
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    InChIKey
    HFNKQEVNSGCOJV-OAHLLOKOSA-N
    2 references
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    25126798
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    stated in
    Q98915402 (Deleted Item)
    ChEMBL ID
    CHEMBL1789941
    1 reference
    stated in
    ChEMBL English
    ChEMBL ID
    CHEMBL1789941
    language of work or name
    English
    title
    RUXOLITINIB (English)
    retrieved
    20 November 2016
    ChEBI ID
    66919
    mapping relation type English
    exact match English
    1 reference
    stated in
    ChEMBL English
    ChEMBL ID
    CHEMBL1789941
    language of work or name
    English
    title
    RUXOLITINIB (English)
    retrieved
    20 November 2016
    ChemSpider ID
    25027389
    1 reference
    stated in
    ChemSpider
    ChemSpider ID
    25027389
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    DrugBank ID English
    08877
    1 reference
    stated in
    Q1122544 (Deleted Item)
    DrugBank ID English
    08877
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    UNII English
    82S8X8XX8H
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    82S8X8XX8H
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    20 November 2016
    ATC code English
    L01XE18
    1 reference
    stated in
    Q1122544 (Deleted Item)
    DrugBank ID English
    08877
    language of work or name
    English
    title
    Ruxolitinib (English)
    publication date
    17 November 2015
    KEGG ID English
    D09959
    1 reference
    stated in
    Q902623 (Deleted Item)
    ChEBI ID
    66919
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    19 October 2016
    Guide to Pharmacology Ligand ID English
    5688
    2 references
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    5688
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    20 November 2016
    retrieved
    22 April 2020
    reference URL
    https://www.guidetopharmacology.org/coronavirus.jsp
    NDF-RT ID English
    N0000184017
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    82S8X8XX8H
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    20 November 2016
    isomeric SMILES
    C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    25126798
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    SMILES
    C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    25126798
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    20 November 2016
    World Health Organisation international non-proprietary name English
    ruxolitinib (English)
    2 references
    stated in
    Q902623 (Deleted Item)
    ChEBI ID
    66919
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    19 October 2016
    published in
    Q75030677 (Deleted Item)
    publication date
    2011
    Reaxys registry number English
    18703668
    1 reference
    stated in
    Q902623 (Deleted Item)
    ChEBI ID
    66919
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    19 October 2016
    PDB structure ID English
    4U5J
    1 reference
    stated in
    Q766195 (Deleted Item)
    PDB structure ID English
    4U5J
    language of work or name
    English
    title
    4U5J (English)
    retrieved
    19 October 2016
    mass
    306.159 http://www.wikidata.org/entity/Q483261
    1 reference
    stated in
    Q278487 (Deleted Item)
    PubChem CID
    25126798
    language of work or name
    English
    title
    Ruxolitinib (English)
    retrieved
    19 October 2016
    UMLS CUI English
    C2931926
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    82S8X8XX8H
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    20 November 2016
    RxNorm ID English
    1193326
    1 reference
    stated in
    Unique Ingredient Identifier English
    UNII English
    82S8X8XX8H
    language of work or name
    English
    title
    ruxolitinib (English)
    retrieved
    20 November 2016
    DSSTox substance ID English
    DTXSID10240930
    1 reference
    stated in
    Q28061352 (Deleted Item)
    Quora topic ID
    Ruxolitinib
    1 reference
    stated in
    Q51711 (Deleted Item)
    active ingredient in English
    Q47521730 (Deleted Item)
    1 reference
    stated in
    RxNorm English
    RxNorm ID English
    1193332
    retrieved
    14 February 2018
    subject has role
    protein kinase inhibitors English
    1 reference
    stated in
    Q21008030 (Deleted Item)
    NDF-RT ID English
    N0000184017
    retrieved
    5 March 2018
    medical condition treated
    thrombogavitis English
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q29496 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    hematopoietic system disease English
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q585285 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q954625 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q948318 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    graft-versus-host disease English
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q933716 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    Q264118 (Deleted Item)
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    myelofibrosis English
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    essential thrombocytosis English
    1 reference
    stated in
    Q56863002 (Deleted Item)
    retrieved
    2 October 2018
    physically interacts with
    Janus kinase 1 English
    subject has role
    Q427492 (Deleted Item)
    1 reference
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    5688
    language of work or name
    English
    retrieved
    17 August 2016
    Q3162114 (Deleted Item)
    subject has role
    Q427492 (Deleted Item)
    1 reference
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    5688
    language of work or name
    English
    retrieved
    17 August 2016
    Janus kinase 3 English
    subject has role
    Q427492 (Deleted Item)
    1 reference
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    5688
    language of work or name
    English
    retrieved
    17 August 2016
    Tyrosine kinase 2 English
    subject has role
    Q427492 (Deleted Item)
    1 reference
    stated in
    Q17091219 (Deleted Item)
    Guide to Pharmacology Ligand ID English
    5688
    language of work or name
    English
    retrieved
    17 August 2016
    LiverTox ID English
    Ruxolitinib
    0 references
    Microsoft Academic ID
    2776112149
    0 references
    DSSTOX compound identifier English
    DTXCID40163421
    0 references
    MESH concept ID
    M0549299
    0 references
    PDB ligand ID English
    RXT
    0 references
    Freebase ID
    /m/0hqvfcr
    0 references
    LiverTox likelihood score English
    Q83284310 (Deleted Item)
    1 reference
    stated in
    Q78239405 (Deleted Item)
    retrieved
    8 April 2021
    reference URL
    https://www.ncbi.nlm.nih.gov/books/n/livertox/Ruxolitinib
    last update English
    2 December 2020
    HSDB ID English
    8259
    1 reference
    stated in
    Hazardous Substances Data Bank
    HSDB ID English
    8259
    publication date
    28 October 2019
    title
    RUXOLITINIB (English)
    retrieved
    10 Mayıs 2021
    MedlinePlus drug identifier English
    a612006
    route of administration English
    Q285166 (Deleted Item)
    0 references
    a621053
    route of administration English
    Q420054 (Deleted Item)
    0 references
    Commons category
    Ruxolitinib
    0 references
    P11199 (Deleted Property)
    PD003424 Property P11199 not found, cannot determine the data type to use.
    0 references
    P11143 (Deleted Property)
    Ruxolitinib Property P11143 not found, cannot determine the data type to use.
    0 references
     
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